Duphaston (Dydrogesterone) is made by Solvay Healthcare Limited.

What is Duphaston?

Duphaston is a synthetic (artificial) progestogen and is similar to the progesterone produced naturally by the ovaries.
Duphaston can also be used in the treatment of:

  • Abnormal uterine bleeding
  • Pre-Menstrual Syndrome
  • Infertility
  • Threatened miscarriage
  • Painful periods
  • Absence of periods

How Duphaston works

The precise action of Duphaston is not fully understood, so is difficult to explain. Duphaston reduces the normal build-up of the uterus lining by oestrogen during the monthly cycle. This action also stops the build-up of endometriosis in other sites. Generally, periods are not stopped and some spotting may occur between periods.

Administration and dosage of Duphaston

Duphaston comes in tablet form in a strength of 10mgs and is taken one, two or three times daily from day five to day twenty-five of the cycle. In some circumstances, especially in the treatment of endometriosis, the treatment is taken continuously, and may be given at higher doses. Treatment is usually for six to twelve months.
Duphaston is not suitable for the treatment of children. It may be used in older women as a form of HRT (Hormone Replacement Therapy).

When Duphaston should not be used (contra-indications)

There are no reported contra-indications for Duphaston.

Precautions in the use of Duphaston

There are no reported risks to pregnancy.
Duphaston is used to prevent threatened abortion.
There have been no reported adverse experiences for lactating (breast-feeding) women.

Reaction of Duphaston with food/alcohol/drugs

None have been reported.

Side effects of Duphaston

  • Nausea
  • Breast tenderness
  • Headache
  • Bloating
  • Dizziness
  • Skin rashes

Breakthrough bleeding between periods may also occur. This can usually be corrected by increasing the dose.
As with all treatments, you may have no side effects at all, or you may experience a few but it is rare to experience multiple side effects.
Do remember to report any side effects to your medical practitioner and ask for advice.

See also

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